IPAC - International Pharmaceutical Aerosol Consortium
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A Message About IPAC
MDI bottom Welcome to our Web Page! We are a group of companies committed to meeting the treatment needs of patients who suffer from asthma and chronic obstructive pulmonary disease (COPD). IPAC represents leading manufacturers of metered-dose inhalers (MDIs), which are widely accepted as one of the most successful delivery methods for medicines which treat respiratory disease. IPAC member companies are now in the forefront of developing a new class of MDIs for respiratory medicines.

The MDI is the mainstay of successful treatment of asthma and other respiratory conditions. After its introduction in the 1950's, the metered-dose inhaler revolutionized the treatment of asthma and COPD. MDIs are pocket-sized devices with propellants which deliver medicine rapidly to the lungs of the patient. Because no other inhalation system provides the same range of benefits, the MDI is the most popular delivery system among inhaled therapies. Over 70 million patients worldwide rely on the device.

Our companies are now reformulating MDIs to replace CFC propellants with ozone-friendly alternatives. While the propellants are being changed, the medicines are the same. We've been focusing our efforts and devoting significant resources to the development of CFC-free MDIs. Companies around the world are testing inhalers which contain ozone-friendly propellants. These new propellants have been found to be safe for patients.

This hard work and investment are now being rewarded. CFC-free MDIs containing asthma medicines have been introduced in many countries around the world, including in the United States and the European Union. Other CFC-free MDIs are awaiting regulatory approval to be marketed and will be introduced within the next several years. This movement away from CFCs will benefit the ozone layer.

By our membership in IPAC, we are demonstrating our commitment to be part of a responsible transition to CFC-free inhalers. We intend to replace CFC MDIs as smoothly as possible, so that patients who rely on MDIs will be able to do so with complete confidence both now and in the future. We believe that a successful transition will be one in which:

  • every patient continues to receive effective treatment;

  • pharmaceutical companies actively pursue the development and introduction of safe and effective CFC-free MDIs;

  • governments promptly approve new product applications and encourage the switch to CFC-free MDIs; and

  • patients and their health care providers reinvigorate their relationship by discussing new treatment options and the transition to CFC-free MDIs.

IPAC will search for constructive ways to achieve these goals through partnerships with patients, health care professionals, and regulators involved in this transition. Ensuring patient care and improving treatment options for patients is our number one goal during this process.
 

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